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Donepezil 120014-06-4 Donepezil 120014-06-4

Donepezil 120014-06-4
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Informasi dasar Donepezil 120014-06-4

Name

Donepezil

Alias

2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

CAS Number

120014-06-4

Molecular Formula

C24H29NO3

Molecular Weight

379.49

Quality Standard

In house

Package Size

5kg/bag, 10kg/bag, according to your requirement

Brief Introduction

Donepezil hydrochloride is a long-acting Alzheimer's disease (AD) in symptomatic treatment drugs.
AD is a kind of memory impairment as the main performance, accompanied by other cognitive
impairment of acquired intelligence decline.


Penggunaan Donepezil 120014-06-4

  • Donepezil hidroklorida adalah inhibitor kolinesterase generasi kedua (ChE), efek terapeutiknya secara reversibel menghambat hidrolisis asam asetilkolin asetilkolinesterase (AchE) yang disebabkan oleh peningkatan kandungan reseptor acetylcholine. Donepezil dan mungkin ada mekanisme lain, termasuk pembuangan efek langsung dari peptida, reseptor neurotransmitter atau saluran Ca2 +. Donepezil untuk demensia tipe Alzheimer ringan sampai sedang.

COA dari Donepezil 120014-06-4

ITEMS

SPECIFICATIONS

RESULTS

APPEARANCE

WHITE OR ALMOST WHITE CRYSTALLINE POWDER

CONFORMS

SOLUBILITY

TO MATCH WORKING STANDARD

CONFORMS

IDENTIFICATION

1) BY UV ABSORPTION,TO MATCH WORKING STANDARD

2) BY IR ABSORPTION,TO MATCH WORKING STANDARD



CONFORMS


CONFORMS

MELTING POINT

86-90℃

87.5-88.5℃

RELATED SUBSTANCE

TOTAL

≤1.0%

0.14%

SINGLE IMPURITY (UNKNOWN)

≤0.80%

<0.8%

LOSS ON DRYING

≤1.0%

0.3%

RESIDUE ON IGNITION

≤0.10%

0.02%

HEAVY METAL

≤10 PPM

<10 PPM

ASSAY

≥99.0%

99.87%

CONCLUSION

CONFORMS TO THE ENTERPRISE STANDARD


MORE_DETAIL Donepezil 120014-06-4

Informasi dasar Donepezil 120014-06-4

Name

Donepezil

Alias

2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

CAS Number

120014-06-4

Molecular Formula

C24H29NO3

Molecular Weight

379.49

Quality Standard

In house

Package Size

5kg/bag, 10kg/bag, according to your requirement

Brief Introduction

Donepezil hydrochloride is a long-acting Alzheimer's disease (AD) in symptomatic treatment drugs.
AD is a kind of memory impairment as the main performance, accompanied by other cognitive
impairment of acquired intelligence decline.


Penggunaan Donepezil 120014-06-4

  • Donepezil hidroklorida adalah inhibitor kolinesterase generasi kedua (ChE), efek terapeutiknya secara reversibel menghambat hidrolisis asam asetilkolin asetilkolinesterase (AchE) yang disebabkan oleh peningkatan kandungan reseptor acetylcholine. Donepezil dan mungkin ada mekanisme lain, termasuk pembuangan efek langsung dari peptida, reseptor neurotransmitter atau saluran Ca2 +. Donepezil untuk demensia tipe Alzheimer ringan sampai sedang.

COA dari Donepezil 120014-06-4

ITEMS

SPECIFICATIONS

RESULTS

APPEARANCE

WHITE OR ALMOST WHITE CRYSTALLINE POWDER

CONFORMS

SOLUBILITY

TO MATCH WORKING STANDARD

CONFORMS

IDENTIFICATION

1) BY UV ABSORPTION,TO MATCH WORKING STANDARD

2) BY IR ABSORPTION,TO MATCH WORKING STANDARD



CONFORMS


CONFORMS

MELTING POINT

86-90℃

87.5-88.5℃

RELATED SUBSTANCE

TOTAL

≤1.0%

0.14%

SINGLE IMPURITY (UNKNOWN)

≤0.80%

<0.8%

LOSS ON DRYING

≤1.0%

0.3%

RESIDUE ON IGNITION

≤0.10%

0.02%

HEAVY METAL

≤10 PPM

<10 PPM

ASSAY

≥99.0%

99.87%

CONCLUSION

CONFORMS TO THE ENTERPRISE STANDARD

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